16/04-2018 07:00:13: (NANO) Nordic Nanovector Presents Preclinical Data at AACR 2018
Oslo, Norway, 16 April 2018
Nordic Nanovector ASA (OSE: NANO) announces that a poster reporting the anti
-tumour effect of Humalutin® (177Lu-conjugated humanized anti-CD37 antibody,
177Lu-NNV003) in preclinical models of non-Hodgkin's lymphoma (NHL) was
presented yesterday at the American Association of Cancer Research (AACR) Annual
Meeting 2018 in Chicago, USA. The company previously announced the publication
of the poster abstract (abstract 848) on 15 March 2018.
The poster was entitled "In vitro and in vivo evaluation of the beta-emitting
lutetium-177 labeled anti-CD37 antibody radionuclide conjugate 177Lu-NNV003 in
DLBCL, CLL and MCL models," and showed that:
In tumour cell lines:
. The unlabelled anti-CD37 antibody (NNV003) kills tumour cells mainly through
an immunological process called antibody dependent cellular cytotoxicity
. Humalutin® (177Lu-NNV003) was found to inhibit tumour cell growth.
In preclinical lymphoma models:
. Humalutin® has shown significant tumour uptake and demonstrated an anti-tumour
effect in all three NHL models (mantle cell lymphoma, diffuse large B-cell
lymphoma and chronic lymphocytic leukaemia).
The poster is available at www.nordicnanovector.com in the section Scientific
For further information, please contact:
IR enquiries Malene Brondberg, VP Investor Relations and Corporate
Cell: +44 7561 431 762
Mark Swallow/David Dible/Isabelle Andrews (Citigate Dewe Rogerson)
Tel: +44 207 638 9571
About Nordic Nanovector
Nordic Nanovector is committed to develop and deliver innovative therapies to
patients to address major unmet medical needs and advance cancer care. The
Company aspires to become a leader in the development of targeted therapies for
Nordic Nanovector's lead clinical-stage candidate is Betalutin®, a novel CD37
-targeting Antibody-Radionuclide-Conjugates (ARC) designed to advance the
treatment of non-Hodgkin's Lymphoma (NHL). NHL is an indication with substantial
unmet medical need, representing a growing market forecast to be worth nearly
USD 20 billion by 2024.
Nordic Nanovector intends to retain marketing rights and to actively participate
in the commercialisation of Betalutin® in core markets.
The Company is also advancing a pipeline of ARCs and other immunotherapies for
multiple cancer indications.
Further information about the Company can be found at www.nordicnanove
Ekstern link: http://www.newsweb.no/index.jsp?messageId=448749
Nyheten er levert av OBI.